yes this is the infamous 7 deadly sins skull I designed in 2009, this skull has been bootlegged.
Similarly, when encountering a Sin while playing as Magdalene, it will say Magdalena VS (Sin Name). Buy The 7 Sins Skull by Joby Cummings as a Art Print. When encountering a Sin while playing ? it will say XXX VS (Sin Name) instead of ? VS (Sin Name). The Seven Deadly Sins are based on the Catholic conception of the seven flaws that bring humans to sinful behavior. Edmund claims that the Seven Deadly Sins are all Isaac. A collection of paintings unleash horror on an unsuspecting family corrupted by the seven deadly sins of greed, envy, gluttony, lust, sloth, pride. Does not have to be done in a single playthrough. 
"The Book Of Sin" - Kill The Seven Deadly Sins. Isaac can bomb the door and walk away from a fight with any Sin if he has flight.Fetus = Wrath, The Virus = Lust, The Inner Eye = Greed, etc.) Some of these items can be dropped when the sin is defeated. There are items that the player can collect throughout the game, giving Isaac similar attacks and effects as the Seven Deadly Sins.However, each of these vices gets ample mention throughout the Bible and other religious books, albeit individually. Magic City 7 Sins anamorphic art by Leon Keer - 3D streetpainting, Street Art by 3D street artist Leon Keer - 3D Streetpainting XL - Anamorphic painting.
Ironically, the seven deadly sins do not appear explicitly in the Bible.
These enemies can appear in normal rooms of The Womb/ Utero and onward but unlike regular bosses, they can drop Pick Ups and Items associated with them when they're defeated (if there are multiple sins in the same room, items spawn when the last one is defeated). The seven deadly sins refer to behaviors and habits that are considered among the most cardinal vices under Christian teachings. The health of the Sin you are facing varies, depending on the current floor you are at.
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